Honda CR-V vs Infiniti QX50: Specs Compared

Running cost over five years: at the EPA's 15,000-mile-a-year assumption the Honda CR-V burns about $1,550 of fuel annually against $2,800 for the Infiniti QX50. That $1,250 yearly gap compounds to roughly $6,250 over five years and $10,000 over eight — often more than the price difference between two trims of the same vehicle, and the single largest running-cost line item separating these two.

City and highway economy: the Honda CR-V leads in both cycles — 43 mpg city and 43 mpg highway against 24 and 31 mpg — so its fuel-efficiency advantage holds whether you commute in traffic or cover long highway miles.

Powertrain choice: the Honda CR-V is recorded with 4 distinct engine configurations (SIDI; Hybrid, SIDI, SIDI; Hybrid;), the Infiniti QX50 with 3 (SIDI & PFI, SIDI & PFI; VCR, 3.7). Across 44 recorded Honda CR-V configurations and 20 for the Infiniti QX50, the wider the engine spread the more the real-world fuel efficiency depends on which version you actually buy, so check the specific model year and drivetrain rather than the headline number.

Drivetrain and class: the Honda CR-V is offered with Front-Wheel Drive, All-Wheel Drive, the Infiniti QX50 with Front-Wheel Drive, All-Wheel Drive, Rear-Wheel Drive. All-wheel drive typically costs one to two mpg combined against the same vehicle in front- or rear-wheel drive, which is worth remembering when the gap between these two is small. The EPA classes them as Small Sport Utility Vehicle 4WD and Small Sport Utility Vehicle 2WD respectively — the class drives the interior volume, cargo space and passenger space each one is measured against.

Tailpipe emissions: at their cleanest configurations the Honda CR-V emits 223 g/mile of CO2 versus 336 g/mile for the Infiniti QX50. Emissions track fuel consumption almost exactly, so the cleaner vehicle here is also the cheaper one to fuel.