Audi A6 vs Mercedes-Benz E-Class: Specs Compared
Also searched as Mercedes-Benz E-Class vs Audi A6 specs — both orientations show this same side-by-side comparison.
The Audi A6 is the more efficient of the two: it reaches 30 mpg combined versus 28 mpg for the Mercedes-Benz E-Class, a 2 mpg advantage and costs about $50 less per year to fuel.
Across 4 measured categories, the Audi A6 leads in 3. Figures are EPA test data, not manufacturer claims.
2015–2027
Mercedes-Benz E-Class
Midsize Cars · 136 configurations
Head-to-head specifications
| Metric | Audi A6 | Mercedes-Benz E-Class |
|---|---|---|
| Best combined MPG | 30 mpg ✓ | 28 mpg |
| Best city MPG | 25 mpg | 25 mpg |
| Best highway MPG | 38 mpg ✓ | 33 mpg |
| Lowest annual fuel costEPA estimate at 15,000 miles per year | $2,650 ✓ | $2,700 |
| Lowest CO2 output | 311 g/mi | 115 g/mi ✓ |
| Engines offered | SIDI, SIDI; Mild Hybrid, 3.0 | SIDI; Mild Hybrid, SIDI; PHEV, SIDI, SIDI; FFV |
| Transmissions | Automatic (AM-S7), Automatic (S8), Automatic (AV-S8) | Automatic 9-spd, Automatic 7-spd |
| Drivetrains | All-Wheel Drive, 4-Wheel Drive, Front-Wheel Drive | All-Wheel Drive, Rear-Wheel Drive, 4-Wheel Drive |
| Fuel types | Premium, Diesel | Premium, Premium and Electricity, Premium or E85 |
| EPA class | Midsize Cars | Midsize Cars |
| Years covered | 2015–2026 | 2015–2027 |
| Configurations on record | 36 | 136 |
Source: EPA fuel economy records via fueleconomy.gov. Best-case values across all recorded configurations for each model.
Audi A6 vs Mercedes-Benz E-Class dimensions and size
The Audi A6 is 1.6 inches longer than the Mercedes-Benz E-Class on a wheelbase 1.6 inches shorter, and 950.2 lbs lighter. Both clear the roughly 200 inches of usable length in a standard single garage bay.
| Dimension | Audi A6 (2026) | Mercedes-Benz E-Class (2026) | Difference |
|---|---|---|---|
| Length | 196.9 in | 195.3 in | 1.6 in |
| Width (excl. mirrors) | 74 in | 74.8 in | 0.8 in |
| Height | 57.5 in | 57.9 in | 0.4 in |
| Wheelbase | 115 in | 116.5 in | 1.6 in |
| Curb weight | 4,319 lbs | 5,269 lbs | 950 lbs |
Width excludes mirrors; add 8–12 inches for mirrors out. Figures are for the newest model year on record for each vehicle. See both drawn to scale.
Audi A6 vs Mercedes-Benz E-Class: what the numbers mean
Running cost over five years: at the EPA's 15,000-mile-a-year assumption the Audi A6 burns about $2,650 of fuel annually against $2,700 for the Mercedes-Benz E-Class. That $50 yearly gap compounds to roughly $250 over five years and $400 over eight — often more than the price difference between two trims of the same vehicle, and the single largest running-cost line item separating these two.
City versus highway split: the Mercedes-Benz E-Class is the stronger commuter at 25 mpg city, while the Audi A6 pulls ahead on the interstate at 38 mpg highway. If most of your driving is stop-and-go traffic the city figure is the one to weigh; for long-distance highway mileage the reverse is true, and the two vehicles effectively swap places depending on how you drive.
Powertrain choice: the Audi A6 is recorded with 3 distinct engine configurations (SIDI, SIDI; Mild Hybrid, 3.0), the Mercedes-Benz E-Class with 4 (SIDI; Mild Hybrid, SIDI; PHEV, SIDI). Across 36 recorded Audi A6 configurations and 136 for the Mercedes-Benz E-Class, the wider the engine spread the more the real-world fuel efficiency depends on which version you actually buy, so check the specific model year and drivetrain rather than the headline number.
Drivetrain and class: the Audi A6 is offered with All-Wheel Drive, 4-Wheel Drive, Front-Wheel Drive, the Mercedes-Benz E-Class with All-Wheel Drive, Rear-Wheel Drive, 4-Wheel Drive. All-wheel drive typically costs one to two mpg combined against the same vehicle in front- or rear-wheel drive, which is worth remembering when the gap between these two is small. The EPA classes them as Midsize Cars and Midsize Cars respectively — the class drives the interior volume, cargo space and passenger space each one is measured against.
Tailpipe emissions: at their cleanest configurations the Mercedes-Benz E-Class emits 115 g/mile of CO2 versus 311 g/mile for the Audi A6. Emissions track fuel consumption almost exactly, so the cleaner vehicle here is also the cheaper one to fuel.
A6 vs E-Class: common questions
Which is better on gas, the Audi A6 or the Mercedes-Benz E-Class?
The Audi A6 is the more efficient of the two: it reaches 30 mpg combined versus 28 mpg for the Mercedes-Benz E-Class, a 2 mpg advantage and costs about $50 less per year to fuel.
Which costs less to run per year?
By EPA estimates at 15,000 miles a year, the Audi A6 runs about $2,650 a year in fuel at its most efficient configuration, versus about $2,700 for the Mercedes-Benz E-Class — a difference of roughly $50 per year.
What engines do the A6 and E-Class offer?
Audi A6: SIDI, SIDI; Mild Hybrid, 3.0. Mercedes-Benz E-Class: SIDI; Mild Hybrid, SIDI; PHEV, SIDI, SIDI; FFV.
Are they in the same vehicle class?
Yes — the EPA classifies both the Audi A6 and the Mercedes-Benz E-Class as Midsize Cars, so they compete directly.
More A6 comparisons
More E-Class comparisons
Comparison id: audi-a6-vs-mercedes-benz-e-class