Lexus NX vs Mercedes-Benz GLC-Class: Specs Compared

Also searched as Mercedes-Benz GLC-Class vs Lexus NX specs — both orientations show this same side-by-side comparison.

The Lexus NX is the more efficient of the two: it reaches 40 mpg combined versus 29 mpg for the Mercedes-Benz GLC-Class, a 11 mpg advantage and costs about $700 less per year to fuel.

Across 5 measured categories, the Lexus NX leads in 4. Figures are EPA test data, not manufacturer claims.

2015–2026

Lexus NX

Small Sport Utility Vehicle 4WD · 58 configurations

40mpg combined (best)
All Lexus NX specs

2016–2027

Mercedes-Benz GLC-Class

Small Sport Utility Vehicle 4WD · 72 configurations

29mpg combined (best)
All Mercedes-Benz GLC-Class specs

Head-to-head specifications

MetricLexus NXMercedes-Benz GLC-Class
Best combined MPG40 mpg ✓29 mpg
Best city MPG42 mpg ✓26 mpg
Best highway MPG38 mpg ✓33 mpg
Lowest annual fuel costEPA estimate at 15,000 miles per year$1,900 ✓$2,600
Lowest CO2 output87 g/mi84 g/mi ✓
Engines offeredSIDI & PFI; Hybrid, SIDI & PFI, SIDI & PFI; PHEV, 2.5SIDI; Mild Hybrid, SIDI; PHEV, SIDI
TransmissionsAutomatic (AV-S6), Automatic (S8), Automatic (S6)Automatic 9-spd, Automatic 7-spd, Automatic (S9)
DrivetrainsFront-Wheel Drive, All-Wheel DriveRear-Wheel Drive, All-Wheel Drive, 4-Wheel Drive
Fuel typesPremium, Regular, Premium and ElectricityPremium, Premium and Electricity
EPA classSmall Sport Utility Vehicle 4WDSmall Sport Utility Vehicle 4WD
Years covered2015–20262016–2027
Configurations on record5872

Source: EPA fuel economy records via fueleconomy.gov. Best-case values across all recorded configurations for each model.

Lexus NX vs Mercedes-Benz GLC-Class: what the numbers mean

Running cost over five years: at the EPA's 15,000-mile-a-year assumption the Lexus NX burns about $1,900 of fuel annually against $2,600 for the Mercedes-Benz GLC-Class. That $700 yearly gap compounds to roughly $3,500 over five years and $5,600 over eight — often more than the price difference between two trims of the same vehicle, and the single largest running-cost line item separating these two.

City and highway economy: the Lexus NX leads in both cycles — 42 mpg city and 38 mpg highway against 26 and 33 mpg — so its fuel-efficiency advantage holds whether you commute in traffic or cover long highway miles.

Powertrain choice: the Lexus NX is recorded with 4 distinct engine configurations (SIDI & PFI; Hybrid, SIDI & PFI, SIDI & PFI; PHEV), the Mercedes-Benz GLC-Class with 3 (SIDI; Mild Hybrid, SIDI; PHEV, SIDI). Across 58 recorded Lexus NX configurations and 72 for the Mercedes-Benz GLC-Class, the wider the engine spread the more the real-world fuel efficiency depends on which version you actually buy, so check the specific model year and drivetrain rather than the headline number.

Drivetrain and class: the Lexus NX is offered with Front-Wheel Drive, All-Wheel Drive, the Mercedes-Benz GLC-Class with Rear-Wheel Drive, All-Wheel Drive, 4-Wheel Drive. All-wheel drive typically costs one to two mpg combined against the same vehicle in front- or rear-wheel drive, which is worth remembering when the gap between these two is small. The EPA classes them as Small Sport Utility Vehicle 4WD and Small Sport Utility Vehicle 4WD respectively — the class drives the interior volume, cargo space and passenger space each one is measured against.

Tailpipe emissions: at their cleanest configurations the Mercedes-Benz GLC-Class emits 84 g/mile of CO2 versus 87 g/mile for the Lexus NX. Emissions track fuel consumption almost exactly, so the cleaner vehicle here is also the cheaper one to fuel.

NX vs GLC-Class: common questions

Which is better on gas, the Lexus NX or the Mercedes-Benz GLC-Class?

The Lexus NX is the more efficient of the two: it reaches 40 mpg combined versus 29 mpg for the Mercedes-Benz GLC-Class, a 11 mpg advantage and costs about $700 less per year to fuel.

Which costs less to run per year?

By EPA estimates at 15,000 miles a year, the Lexus NX runs about $1,900 a year in fuel at its most efficient configuration, versus about $2,600 for the Mercedes-Benz GLC-Class — a difference of roughly $700 per year.

What engines do the NX and GLC-Class offer?

Lexus NX: SIDI & PFI; Hybrid, SIDI & PFI, SIDI & PFI; PHEV, 2.5. Mercedes-Benz GLC-Class: SIDI; Mild Hybrid, SIDI; PHEV, SIDI.

Are they in the same vehicle class?

Yes — the EPA classifies both the Lexus NX and the Mercedes-Benz GLC-Class as Small Sport Utility Vehicle 4WD, so they compete directly.

More NX comparisons

More GLC-Class comparisons

Comparison id: lexus-nx-vs-mercedes-benz-glc-class