Ford Mustang vs Mercedes-Benz CLS-Class: Specs Compared

Running cost over five years: at the EPA's 15,000-mile-a-year assumption the Ford Mustang burns about $2,350 of fuel annually against $2,900 for the Mercedes-Benz CLS-Class. That $550 yearly gap compounds to roughly $2,750 over five years and $4,400 over eight — often more than the price difference between two trims of the same vehicle, and the single largest running-cost line item separating these two.

City versus highway split: the Mercedes-Benz CLS-Class is the stronger commuter at 24 mpg city, while the Ford Mustang pulls ahead on the interstate at 33 mpg highway. If most of your driving is stop-and-go traffic the city figure is the one to weigh; for long-distance highway mileage the reverse is true, and the two vehicles effectively swap places depending on how you drive.

Powertrain choice: the Ford Mustang is recorded with 4 distinct engine configurations (5.2, 5.0, SIDI & PFI), the Mercedes-Benz CLS-Class with 2 (SIDI; Mild Hybrid, SIDI). Across 133 recorded Ford Mustang configurations and 27 for the Mercedes-Benz CLS-Class, the wider the engine spread the more the real-world fuel efficiency depends on which version you actually buy, so check the specific model year and drivetrain rather than the headline number.

Drivetrain and class: the Ford Mustang is offered with Rear-Wheel Drive, the Mercedes-Benz CLS-Class with All-Wheel Drive, 4-Wheel Drive, Rear-Wheel Drive. All-wheel drive typically costs one to two mpg combined against the same vehicle in front- or rear-wheel drive, which is worth remembering when the gap between these two is small. The EPA classes them as Subcompact Cars and Compact Cars respectively — the class drives the interior volume, cargo space and passenger space each one is measured against.

Tailpipe emissions: at their cleanest configurations the Mercedes-Benz CLS-Class emits 334 g/mile of CO2 versus 341 g/mile for the Ford Mustang. Emissions track fuel consumption almost exactly, so the cleaner vehicle here is also the cheaper one to fuel.