Cadillac CT5 vs Mercedes-Benz CLS-Class: Specs Compared

Also searched as Mercedes-Benz CLS-Class vs Cadillac CT5 specs — both orientations show this same side-by-side comparison.

The Cadillac CT5 is the more efficient of the two: it reaches 27 mpg combined versus 26 mpg for the Mercedes-Benz CLS-Class, a 1 mpg advantage and costs about $100 less per year to fuel.

Across 5 measured categories, the Cadillac CT5 leads in 4. Figures are EPA test data, not manufacturer claims.

2020–2026

Cadillac CT5

Midsize Cars · 52 configurations

27mpg combined (best)
All Cadillac CT5 specs

2015–2023

Mercedes-Benz CLS-Class

Compact Cars · 27 configurations

26mpg combined (best)
All Mercedes-Benz CLS-Class specs

Head-to-head specifications

MetricCadillac CT5Mercedes-Benz CLS-Class
Best combined MPG27 mpg ✓26 mpg
Best city MPG23 mpg24 mpg ✓
Best highway MPG33 mpg ✓31 mpg
Lowest annual fuel costEPA estimate at 15,000 miles per year$2,800 ✓$2,900
Lowest CO2 output333 g/mi ✓334 g/mi
Engines offeredSIDISIDI; Mild Hybrid, SIDI
TransmissionsAutomatic (S10), Manual 6-spdAutomatic 9-spd, Automatic 7-spd
DrivetrainsAll-Wheel Drive, Rear-Wheel DriveAll-Wheel Drive, 4-Wheel Drive, Rear-Wheel Drive
Fuel typesPremiumPremium
EPA classMidsize CarsCompact Cars
Years covered2020–20262015–2023
Configurations on record5227

Source: EPA fuel economy records via fueleconomy.gov. Best-case values across all recorded configurations for each model.

Cadillac CT5 vs Mercedes-Benz CLS-Class dimensions and size

The Mercedes-Benz CLS-Class is 0.8 inches longer than the Cadillac CT5 on a wheelbase 3.1 inches shorter, and 478.4 lbs heavier. Both clear the roughly 200 inches of usable length in a standard single garage bay.

Cadillac CT5 versus Mercedes-Benz CLS-Class exterior dimensions
DimensionCadillac CT5 (2026)Mercedes-Benz CLS-Class (2018)Difference
Length193.7 in194.5 in0.8 in
Width (excl. mirrors)74 in74 inidentical
Height57.1 in55.9 in1.2 in
Wheelbase116.1 in113 in3.1 in
Curb weight3,799 lbs4,277 lbs478 lbs

Width excludes mirrors; add 8–12 inches for mirrors out. Figures are for the newest model year on record for each vehicle. See both drawn to scale.

Cadillac CT5 vs Mercedes-Benz CLS-Class: what the numbers mean

Running cost over five years: at the EPA's 15,000-mile-a-year assumption the Cadillac CT5 burns about $2,800 of fuel annually against $2,900 for the Mercedes-Benz CLS-Class. That $100 yearly gap compounds to roughly $500 over five years and $800 over eight — often more than the price difference between two trims of the same vehicle, and the single largest running-cost line item separating these two.

City versus highway split: the Mercedes-Benz CLS-Class is the stronger commuter at 24 mpg city, while the Cadillac CT5 pulls ahead on the interstate at 33 mpg highway. If most of your driving is stop-and-go traffic the city figure is the one to weigh; for long-distance highway mileage the reverse is true, and the two vehicles effectively swap places depending on how you drive.

Powertrain choice: the Cadillac CT5 is recorded with 1 distinct engine configuration (SIDI), the Mercedes-Benz CLS-Class with 2 (SIDI; Mild Hybrid, SIDI). Across 52 recorded Cadillac CT5 configurations and 27 for the Mercedes-Benz CLS-Class, the wider the engine spread the more the real-world fuel efficiency depends on which version you actually buy, so check the specific model year and drivetrain rather than the headline number.

Drivetrain and class: the Cadillac CT5 is offered with All-Wheel Drive, Rear-Wheel Drive, the Mercedes-Benz CLS-Class with All-Wheel Drive, 4-Wheel Drive, Rear-Wheel Drive. All-wheel drive typically costs one to two mpg combined against the same vehicle in front- or rear-wheel drive, which is worth remembering when the gap between these two is small. The EPA classes them as Midsize Cars and Compact Cars respectively — the class drives the interior volume, cargo space and passenger space each one is measured against.

Tailpipe emissions: at their cleanest configurations the Cadillac CT5 emits 333 g/mile of CO2 versus 334 g/mile for the Mercedes-Benz CLS-Class. Emissions track fuel consumption almost exactly, so the cleaner vehicle here is also the cheaper one to fuel.

CT5 vs CLS-Class: common questions

Which is better on gas, the Cadillac CT5 or the Mercedes-Benz CLS-Class?

The Cadillac CT5 is the more efficient of the two: it reaches 27 mpg combined versus 26 mpg for the Mercedes-Benz CLS-Class, a 1 mpg advantage and costs about $100 less per year to fuel.

Which costs less to run per year?

By EPA estimates at 15,000 miles a year, the Cadillac CT5 runs about $2,800 a year in fuel at its most efficient configuration, versus about $2,900 for the Mercedes-Benz CLS-Class — a difference of roughly $100 per year.

What engines do the CT5 and CLS-Class offer?

Cadillac CT5: SIDI. Mercedes-Benz CLS-Class: SIDI; Mild Hybrid, SIDI.

Are they in the same vehicle class?

The EPA classifies the Cadillac CT5 as Midsize Cars and the Mercedes-Benz CLS-Class as Compact Cars, so they aren't a like-for-like match on size.

More CT5 comparisons

More CLS-Class comparisons

Comparison id: cadillac-ct5-vs-mercedes-benz-cls-class