Buick Enclave vs Mercedes-Benz GLS-Class: Specs Compared

Also searched as Mercedes-Benz GLS-Class vs Buick Enclave specs — both orientations show this same side-by-side comparison.

The Buick Enclave is the more efficient of the two: it reaches 23 mpg combined versus 21 mpg for the Mercedes-Benz GLS-Class, a 2 mpg advantage and costs about $950 less per year to fuel.

Across 4 measured categories, the Buick Enclave leads in 4. Figures are EPA test data, not manufacturer claims.

2015–2027

Buick Enclave

Standard Sport Utility Vehicle 4WD · 26 configurations

23mpg combined (best)
All Buick Enclave specs

2017–2026

Mercedes-Benz GLS-Class

Standard Sport Utility Vehicle 4WD · 35 configurations

21mpg combined (best)
All Mercedes-Benz GLS-Class specs

Head-to-head specifications

MetricBuick EnclaveMercedes-Benz GLS-Class
Best combined MPG23 mpg ✓21 mpg
Best city MPG20 mpg20 mpg
Best highway MPG27 mpg ✓24 mpg
Lowest annual fuel costEPA estimate at 15,000 miles per year$2,650 ✓$3,600
Lowest CO2 output387 g/mi ✓414 g/mi
Engines offeredSIDISIDI; Mild Hybrid, SIDI
TransmissionsAutomatic 8-spd, Automatic 9-spd, Automatic 6-spdAutomatic 9-spd, Automatic 7-spd
DrivetrainsAll-Wheel Drive, Front-Wheel DriveAll-Wheel Drive, 4-Wheel Drive
Fuel typesRegularPremium
EPA classStandard Sport Utility Vehicle 4WDStandard Sport Utility Vehicle 4WD
Years covered2015–20272017–2026
Configurations on record2635

Source: EPA fuel economy records via fueleconomy.gov. Best-case values across all recorded configurations for each model.

Buick Enclave vs Mercedes-Benz GLS-Class dimensions and size

The Buick Enclave is 1.6 inches longer than the Mercedes-Benz GLS-Class on a wheelbase 2.4 inches shorter, and 1,340.4 lbs lighter. At over 200 inches, the larger of the two is past the comfortable limit of a standard 192-inch single garage bay once you allow walking room.

Buick Enclave versus Mercedes-Benz GLS-Class exterior dimensions
DimensionBuick Enclave (2026)Mercedes-Benz GLS-Class (2026)Difference
Length207.5 in205.9 in1.6 in
Width (excl. mirrors)79.5 in79.9 in0.4 in
Height70.9 in71.7 in0.8 in
Wheelbase120.9 in123.2 in2.4 in
Curb weight4,733 lbs6,074 lbs1,340 lbs

Width excludes mirrors; add 8–12 inches for mirrors out. Figures are for the newest model year on record for each vehicle. See both drawn to scale.

Buick Enclave vs Mercedes-Benz GLS-Class: what the numbers mean

Running cost over five years: at the EPA's 15,000-mile-a-year assumption the Buick Enclave burns about $2,650 of fuel annually against $3,600 for the Mercedes-Benz GLS-Class. That $950 yearly gap compounds to roughly $4,750 over five years and $7,600 over eight — often more than the price difference between two trims of the same vehicle, and the single largest running-cost line item separating these two.

City versus highway split: the Mercedes-Benz GLS-Class is the stronger commuter at 20 mpg city, while the Buick Enclave pulls ahead on the interstate at 27 mpg highway. If most of your driving is stop-and-go traffic the city figure is the one to weigh; for long-distance highway mileage the reverse is true, and the two vehicles effectively swap places depending on how you drive.

Powertrain choice: the Buick Enclave is recorded with 1 distinct engine configuration (SIDI), the Mercedes-Benz GLS-Class with 2 (SIDI; Mild Hybrid, SIDI). Across 26 recorded Buick Enclave configurations and 35 for the Mercedes-Benz GLS-Class, the wider the engine spread the more the real-world fuel efficiency depends on which version you actually buy, so check the specific model year and drivetrain rather than the headline number.

Drivetrain and class: the Buick Enclave is offered with All-Wheel Drive, Front-Wheel Drive, the Mercedes-Benz GLS-Class with All-Wheel Drive, 4-Wheel Drive. All-wheel drive typically costs one to two mpg combined against the same vehicle in front- or rear-wheel drive, which is worth remembering when the gap between these two is small. The EPA classes them as Standard Sport Utility Vehicle 4WD and Standard Sport Utility Vehicle 4WD respectively — the class drives the interior volume, cargo space and passenger space each one is measured against.

Tailpipe emissions: at their cleanest configurations the Buick Enclave emits 387 g/mile of CO2 versus 414 g/mile for the Mercedes-Benz GLS-Class. Emissions track fuel consumption almost exactly, so the cleaner vehicle here is also the cheaper one to fuel.

Enclave vs GLS-Class: common questions

Which is better on gas, the Buick Enclave or the Mercedes-Benz GLS-Class?

The Buick Enclave is the more efficient of the two: it reaches 23 mpg combined versus 21 mpg for the Mercedes-Benz GLS-Class, a 2 mpg advantage and costs about $950 less per year to fuel.

Which costs less to run per year?

By EPA estimates at 15,000 miles a year, the Buick Enclave runs about $2,650 a year in fuel at its most efficient configuration, versus about $3,600 for the Mercedes-Benz GLS-Class — a difference of roughly $950 per year.

What engines do the Enclave and GLS-Class offer?

Buick Enclave: SIDI. Mercedes-Benz GLS-Class: SIDI; Mild Hybrid, SIDI.

Are they in the same vehicle class?

Yes — the EPA classifies both the Buick Enclave and the Mercedes-Benz GLS-Class as Standard Sport Utility Vehicle 4WD, so they compete directly.

More Enclave comparisons

More GLS-Class comparisons

Comparison id: buick-enclave-vs-mercedes-benz-gls-class