Lexus LS vs Mercedes-Benz CLE-Class: Specs Compared

Also searched as Mercedes-Benz CLE-Class vs Lexus LS specs — both orientations show this same side-by-side comparison.

The Lexus LS and Mercedes-Benz CLE-Class are evenly matched on fuel economy — both peak at 28 mpg combined — so the decision comes down to engine choice, drivetrain, and class.

Across 3 measured categories, the Lexus LS leads in 2. Figures are EPA test data, not manufacturer claims.

2015–2026

Lexus LS

Midsize Cars · 47 configurations

28mpg combined (best)
All Lexus LS specs

2024–2027

Mercedes-Benz CLE-Class

Subcompact Cars · 23 configurations

28mpg combined (best)
All Mercedes-Benz CLE-Class specs

Head-to-head specifications

MetricLexus LSMercedes-Benz CLE-Class
Best combined MPG28 mpg28 mpg
Best city MPG25 mpg ✓24 mpg
Best highway MPG33 mpg34 mpg ✓
Lowest annual fuel costEPA estimate at 15,000 miles per year$2,700$2,700
Lowest CO2 output314 g/mi ✓323 g/mi
Engines offeredSIDI & PFI, SIDI & PFI; Hybrid; with ADS, SIDI & PFI; HybridSIDI; Mild Hybrid
TransmissionsAutomatic (S10), Automatic (AV-S10), Automatic (S8)Automatic 9-spd
DrivetrainsAll-Wheel Drive, Rear-Wheel DriveAll-Wheel Drive
Fuel typesPremiumPremium
EPA classMidsize CarsSubcompact Cars
Years covered2015–20262024–2027
Configurations on record4723

Source: EPA fuel economy records via fueleconomy.gov. Best-case values across all recorded configurations for each model.

Lexus LS vs Mercedes-Benz CLE-Class: what the numbers mean

Running cost over five years: at the EPA's 15,000-mile-a-year assumption the Lexus LS burns about $2,700 of fuel annually against $2,700 for the Mercedes-Benz CLE-Class. That $0 yearly gap compounds to roughly $0 over five years and $0 over eight — often more than the price difference between two trims of the same vehicle, and the single largest running-cost line item separating these two.

City versus highway split: the Lexus LS is the stronger commuter at 25 mpg city, while the Mercedes-Benz CLE-Class pulls ahead on the interstate at 34 mpg highway. If most of your driving is stop-and-go traffic the city figure is the one to weigh; for long-distance highway mileage the reverse is true, and the two vehicles effectively swap places depending on how you drive.

Powertrain choice: the Lexus LS is recorded with 3 distinct engine configurations (SIDI & PFI, SIDI & PFI; Hybrid; with ADS, SIDI & PFI; Hybrid), the Mercedes-Benz CLE-Class with 1 (SIDI; Mild Hybrid). Across 47 recorded Lexus LS configurations and 23 for the Mercedes-Benz CLE-Class, the wider the engine spread the more the real-world fuel efficiency depends on which version you actually buy, so check the specific model year and drivetrain rather than the headline number.

Drivetrain and class: the Lexus LS is offered with All-Wheel Drive, Rear-Wheel Drive, the Mercedes-Benz CLE-Class with All-Wheel Drive. All-wheel drive typically costs one to two mpg combined against the same vehicle in front- or rear-wheel drive, which is worth remembering when the gap between these two is small. The EPA classes them as Midsize Cars and Subcompact Cars respectively — the class drives the interior volume, cargo space and passenger space each one is measured against.

Tailpipe emissions: at their cleanest configurations the Lexus LS emits 314 g/mile of CO2 versus 323 g/mile for the Mercedes-Benz CLE-Class. Emissions track fuel consumption almost exactly, so the cleaner vehicle here is also the cheaper one to fuel.

LS vs CLE-Class: common questions

Which is better on gas, the Lexus LS or the Mercedes-Benz CLE-Class?

The Lexus LS and Mercedes-Benz CLE-Class are evenly matched on fuel economy — both peak at 28 mpg combined — so the decision comes down to engine choice, drivetrain, and class.

Which costs less to run per year?

By EPA estimates at 15,000 miles a year, the Mercedes-Benz CLE-Class runs about $2,700 a year in fuel at its most efficient configuration, versus about $2,700 for the Lexus LS — a difference of roughly $0 per year.

What engines do the LS and CLE-Class offer?

Lexus LS: SIDI & PFI, SIDI & PFI; Hybrid; with ADS, SIDI & PFI; Hybrid. Mercedes-Benz CLE-Class: SIDI; Mild Hybrid.

Are they in the same vehicle class?

The EPA classifies the Lexus LS as Midsize Cars and the Mercedes-Benz CLE-Class as Subcompact Cars, so they aren't a like-for-like match on size.

More LS comparisons

More CLE-Class comparisons

Comparison id: lexus-ls-vs-mercedes-benz-cle-class