Infiniti Q50 vs Lexus IS
The Infiniti Q50 is the more efficient of the two: it reaches 31 mpg combined versus 26 mpg for the Lexus IS, a 5 mpg advantage and costs about $450 less per year to fuel.
Across 5 measured categories, the Infiniti Q50 leads in 5. Figures are EPA test data, not manufacturer claims.
Head-to-head specifications
| Metric | Infiniti Q50 | Lexus IS |
|---|---|---|
| Best combined MPG | 31 mpg ✓ | 26 mpg |
| Best city MPG | 29 mpg ✓ | 22 mpg |
| Best highway MPG | 36 mpg ✓ | 32 mpg |
| Lowest annual fuel costEPA estimate at 15,000 miles per year | $2,450 ✓ | $2,900 |
| Lowest CO2 output | 286 g/mi ✓ | 345 g/mi |
| Engines offered | SIDI, 3.5, 2.0, 3.7 | SIDI & PFI, SIDI |
| Transmissions | Automatic (S7) | Automatic (S6), Automatic (S8) |
| Drivetrains | All-Wheel Drive, Rear-Wheel Drive | All-Wheel Drive, Rear-Wheel Drive |
| Fuel types | Premium | Premium |
| EPA class | Midsize Cars | Compact Cars |
| Years covered | 2015–2024 | 2015–2026 |
| Configurations on record | 60 | 52 |
Source: EPA fuel economy records via fueleconomy.gov. Best-case values across all recorded configurations for each model.
Q50 vs IS: common questions
Which is better on gas, the Infiniti Q50 or the Lexus IS?
The Infiniti Q50 is the more efficient of the two: it reaches 31 mpg combined versus 26 mpg for the Lexus IS, a 5 mpg advantage and costs about $450 less per year to fuel.
Which costs less to run per year?
By EPA estimates at 15,000 miles a year, the Infiniti Q50 runs about $2,450 a year in fuel at its most efficient configuration, versus about $2,900 for the Lexus IS — a difference of roughly $450 per year.
What engines do the Q50 and IS offer?
Infiniti Q50: SIDI, 3.5, 2.0, 3.7. Lexus IS: SIDI & PFI, SIDI.
Are they in the same vehicle class?
The EPA classifies the Infiniti Q50 as Midsize Cars and the Lexus IS as Compact Cars, so they aren't a like-for-like match on size.
More Q50 comparisons
Comparison id: infiniti-q50-vs-lexus-is