Honda Odyssey vs Toyota Sienna
The Toyota Sienna is the more efficient of the two: it reaches 36 mpg combined versus 22 mpg for the Honda Odyssey, a 14 mpg advantage and costs about $1,100 less per year to fuel.
Across 5 measured categories, the Toyota Sienna leads in 5. Figures are EPA test data, not manufacturer claims.
Head-to-head specifications
| Metric | Honda Odyssey | Toyota Sienna |
|---|---|---|
| Best combined MPG | 22 mpg | 36 mpg ✓ |
| Best city MPG | 19 mpg | 36 mpg ✓ |
| Best highway MPG | 28 mpg | 36 mpg ✓ |
| Lowest annual fuel costEPA estimate at 15,000 miles per year | $2,800 | $1,700 ✓ |
| Lowest CO2 output | 394 g/mi | 246 g/mi ✓ |
| Engines offered | SIDI, 3.5 | SIDI & PFI; Hybrid, SIDI & PFI, 3.5 |
| Transmissions | Automatic (S10), Automatic 10-spd, Automatic (S9) | Automatic (AV-S6), Automatic (S8), Automatic (S6) |
| Drivetrains | Front-Wheel Drive | Front-Wheel Drive, All-Wheel Drive |
| Fuel types | Regular | Regular |
| EPA class | Minivan - 2WD | Minivan - 2WD |
| Years covered | 2015–2026 | 2015–2026 |
| Configurations on record | 14 | 24 |
Source: EPA fuel economy records via fueleconomy.gov. Best-case values across all recorded configurations for each model.
Odyssey vs Sienna: common questions
Which is better on gas, the Honda Odyssey or the Toyota Sienna?
The Toyota Sienna is the more efficient of the two: it reaches 36 mpg combined versus 22 mpg for the Honda Odyssey, a 14 mpg advantage and costs about $1,100 less per year to fuel.
Which costs less to run per year?
By EPA estimates at 15,000 miles a year, the Toyota Sienna runs about $1,700 a year in fuel at its most efficient configuration, versus about $2,800 for the Honda Odyssey — a difference of roughly $1,100 per year.
What engines do the Odyssey and Sienna offer?
Honda Odyssey: SIDI, 3.5. Toyota Sienna: SIDI & PFI; Hybrid, SIDI & PFI, 3.5.
Are they in the same vehicle class?
Yes — the EPA classifies both the Honda Odyssey and the Toyota Sienna as Minivan - 2WD, so they compete directly.
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Comparison id: honda-odyssey-vs-toyota-sienna