Honda Odyssey vs Nissan Quest
The Honda Odyssey and Nissan Quest are evenly matched on fuel economy — both peak at 22 mpg combined — so the decision comes down to engine choice, drivetrain, and class.
Across 3 measured categories, the Honda Odyssey leads in 2. Figures are EPA test data, not manufacturer claims.
Head-to-head specifications
| Metric | Honda Odyssey | Nissan Quest |
|---|---|---|
| Best combined MPG | 22 mpg | 22 mpg |
| Best city MPG | 19 mpg | 20 mpg ✓ |
| Best highway MPG | 28 mpg ✓ | 27 mpg |
| Lowest annual fuel costEPA estimate at 15,000 miles per year | $2,800 | $2,800 |
| Lowest CO2 output | 394 g/mi ✓ | 396 g/mi |
| Engines offered | SIDI, 3.5 | 3.5 |
| Transmissions | Automatic (S10), Automatic 10-spd, Automatic (S9) | Automatic (variable gear ratios) |
| Drivetrains | Front-Wheel Drive | Front-Wheel Drive |
| Fuel types | Regular | Regular |
| EPA class | Minivan - 2WD | Minivan - 2WD |
| Years covered | 2015–2026 | 2015–2017 |
| Configurations on record | 14 | 3 |
Source: EPA fuel economy records via fueleconomy.gov. Best-case values across all recorded configurations for each model.
Odyssey vs Quest: common questions
Which is better on gas, the Honda Odyssey or the Nissan Quest?
The Honda Odyssey and Nissan Quest are evenly matched on fuel economy — both peak at 22 mpg combined — so the decision comes down to engine choice, drivetrain, and class.
Which costs less to run per year?
By EPA estimates at 15,000 miles a year, the Nissan Quest runs about $2,800 a year in fuel at its most efficient configuration, versus about $2,800 for the Honda Odyssey — a difference of roughly $0 per year.
What engines do the Odyssey and Quest offer?
Honda Odyssey: SIDI, 3.5. Nissan Quest: 3.5.
Are they in the same vehicle class?
Yes — the EPA classifies both the Honda Odyssey and the Nissan Quest as Minivan - 2WD, so they compete directly.
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Comparison id: honda-odyssey-vs-nissan-quest