Toyota Camry vs Mercedes-Benz E-Class
The Toyota Camry is the more efficient of the two: it reaches 52 mpg combined versus 28 mpg for the Mercedes-Benz E-Class, a 24 mpg advantage and costs about $1,500 less per year to fuel.
Across 5 measured categories, the Toyota Camry leads in 4. Figures are EPA test data, not manufacturer claims.
2015–2027
Mercedes-Benz E-Class
Midsize Cars · 136 configurations
Head-to-head specifications
| Metric | Toyota Camry | Mercedes-Benz E-Class |
|---|---|---|
| Best combined MPG | 52 mpg ✓ | 28 mpg |
| Best city MPG | 53 mpg ✓ | 25 mpg |
| Best highway MPG | 53 mpg ✓ | 33 mpg |
| Lowest annual fuel costEPA estimate at 15,000 miles per year | $1,200 ✓ | $2,700 |
| Lowest CO2 output | 170 g/mi | 115 g/mi ✓ |
| Engines offered | SIDI & PFI; Hybrid, SIDI & PFI, 3-mode (Spt/Normal/Eco), 3.5 | SIDI; Mild Hybrid, SIDI; PHEV, SIDI, SIDI; FFV |
| Transmissions | Automatic (AV-S6), Automatic (S8), Automatic (S6) | Automatic 9-spd, Automatic 7-spd |
| Drivetrains | All-Wheel Drive, Front-Wheel Drive | All-Wheel Drive, Rear-Wheel Drive, 4-Wheel Drive |
| Fuel types | Regular | Premium, Premium and Electricity, Premium or E85 |
| EPA class | Midsize Cars | Midsize Cars |
| Years covered | 2015–2026 | 2015–2027 |
| Configurations on record | 83 | 136 |
Source: EPA fuel economy records via fueleconomy.gov. Best-case values across all recorded configurations for each model.
Camry vs E-Class: common questions
Which is better on gas, the Toyota Camry or the Mercedes-Benz E-Class?
The Toyota Camry is the more efficient of the two: it reaches 52 mpg combined versus 28 mpg for the Mercedes-Benz E-Class, a 24 mpg advantage and costs about $1,500 less per year to fuel.
Which costs less to run per year?
By EPA estimates at 15,000 miles a year, the Toyota Camry runs about $1,200 a year in fuel at its most efficient configuration, versus about $2,700 for the Mercedes-Benz E-Class — a difference of roughly $1,500 per year.
What engines do the Camry and E-Class offer?
Toyota Camry: SIDI & PFI; Hybrid, SIDI & PFI, 3-mode (Spt/Normal/Eco), 3.5. Mercedes-Benz E-Class: SIDI; Mild Hybrid, SIDI; PHEV, SIDI, SIDI; FFV.
Are they in the same vehicle class?
Yes — the EPA classifies both the Toyota Camry and the Mercedes-Benz E-Class as Midsize Cars, so they compete directly.
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Comparison id: toyota-camry-vs-mercedes-benz-e-class