Porsche Panamera vs Mercedes-Benz S-Class
The Mercedes-Benz S-Class is the more efficient of the two: it reaches 26 mpg combined versus 25 mpg for the Porsche Panamera, a 1 mpg advantage and costs about $150 less per year to fuel.
Across 5 measured categories, the Mercedes-Benz S-Class leads in 5. Figures are EPA test data, not manufacturer claims.
2015–2026
Porsche Panamera
Large Cars · 139 configurations
2015–2027
Mercedes-Benz S-Class
Large Cars · 106 configurations
Head-to-head specifications
| Metric | Porsche Panamera | Mercedes-Benz S-Class |
|---|---|---|
| Best combined MPG | 25 mpg | 26 mpg ✓ |
| Best city MPG | 23 mpg | 24 mpg ✓ |
| Best highway MPG | 29 mpg | 31 mpg ✓ |
| Lowest annual fuel costEPA estimate at 15,000 miles per year | $3,050 | $2,900 ✓ |
| Lowest CO2 output | 185 g/mi | 106 g/mi ✓ |
| Engines offered | SIDI, SIDI; PHEV, 2.9, 4.0 | SIDI; Mild Hybrid, 6.0, SIDI; PHEV, SIDI |
| Transmissions | Automatic (AM-S8), Automatic (AM-S7) | Automatic 9-spd, Automatic 7-spd |
| Drivetrains | All-Wheel Drive, Rear-Wheel Drive, 4-Wheel Drive | All-Wheel Drive, 4-Wheel Drive, Rear-Wheel Drive |
| Fuel types | Premium, Premium and Electricity, Premium Gas or Electricity | Premium, Premium and Electricity |
| EPA class | Large Cars | Large Cars |
| Years covered | 2015–2026 | 2015–2027 |
| Configurations on record | 139 | 106 |
Source: EPA fuel economy records via fueleconomy.gov. Best-case values across all recorded configurations for each model.
Panamera vs S-Class: common questions
Which is better on gas, the Porsche Panamera or the Mercedes-Benz S-Class?
The Mercedes-Benz S-Class is the more efficient of the two: it reaches 26 mpg combined versus 25 mpg for the Porsche Panamera, a 1 mpg advantage and costs about $150 less per year to fuel.
Which costs less to run per year?
By EPA estimates at 15,000 miles a year, the Mercedes-Benz S-Class runs about $2,900 a year in fuel at its most efficient configuration, versus about $3,050 for the Porsche Panamera — a difference of roughly $150 per year.
What engines do the Panamera and S-Class offer?
Porsche Panamera: SIDI, SIDI; PHEV, 2.9, 4.0. Mercedes-Benz S-Class: SIDI; Mild Hybrid, 6.0, SIDI; PHEV, SIDI.
Are they in the same vehicle class?
Yes — the EPA classifies both the Porsche Panamera and the Mercedes-Benz S-Class as Large Cars, so they compete directly.
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Comparison id: porsche-panamera-vs-mercedes-benz-s-class